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Section: Main.MEDICINE.Gene. Therapy.Hypoxia..Response Element (HRE).Patent..Literature.Claim 1: Nucleic Acid Construct.Comprise: Hypoxia Response Element.(HRE): PhosphoGlycerate Kinase.(PGK) Seq.: -523 - -21 Nucleotide.of Mouse PGK-1 Gene which is.423 - 925 Nucleotide - SEQ ID No. 4.Linked to Coding Seq. Other Than.Mouse PGK-1 Coding Seq..Claim 5: HRE: Lactate DeHydrogenase.(LDH) Seq.: -186 - +47 Nucleotide.of Mouse LDH-A Gene which is.932 - 1164 Nucleotide of SEQ No. 5.Linked to Coding Seq. Other Than.Mouse LDH-A Coding Seq..Claim 11: Gene Product is Enzyme.Converting ProDrug to Active Drug..Claim 12 Enzyme: Cytosine Deaminase.Claim 13: Gene Product: Cytokine.Patent Assignee
Code: 52444
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