Section: |
Main.PHARMA..Chiral Pharmaceuticals.Free Radical Chemistry.Tin (Stannane) Chemistry (-78C).(D)-AminoAcids.(D)-Tert-Leucine..Benzyl N-Tri-F-Acetyl-D-Tert.Leucinate+MgBr2 (Br Introduction).+DiMenthyl-Ph-Tin Hydride Enantiome.r Catalyst at -78C Converted to.(D) Form in 80% Yield & ee > 99% |