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Section:	Main.PSYCHIATRY.Depression.Treatment.Milnacipran.NonGeneric Milnacipran.Patent.Claims.Claim 1: Prolonged-Release Compn.. Combi. Plurality of MiniGranules;.Each MiniGranule Contg MiniSphere.of Milnacipran Coated with Film of.Polymer InSoluble in Water but.Permeable to Physiological Fluids.Thickness=20-100 .mu.m. Oral Adm.MultiParticulate Unit Dosage Form.In Vitro Dissolution Profile Measur.ed by USP XXIII Monograph,.DISSOLUTION, with Paddle Apparatus.Type 2, Speed of Paddles=120 RPM.Dissolution Medium=Phosphate Buffer.(0.066M) pH=7.2; Profile is:.10-55; 40-75; 70-90 & 80-100% of.Dose Release in 2,4,8,12 Hours resp.Claim 2: MiniSphere: 150-1000 mu.g.of Milnacipran. Claim 3: Nonpareils.Claim 4: Nonpareils: Mixt of.75% Sucrose & 25% Starch. Claim 6:.Binder: PVP. Assignee
Code:	61401
Product:	France. P
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