| OBSERVATION'S |
A blood-sucking insect that detoxifies free heme (a cytotoxic iron-porphyrin complex) by polymn it into hemozoin has been identified by researchers in Brazil. FTIR spectra of the polymer isolated from insect are similar to those of malarial hemozoin. The malaria-causing parasite survives in red blood cells by ingesting & degrading hemoglobin, a process that releases free heme. Lacking the enzymes to degrade heme, the malaria parasite forms hemozoin. In "R. prolixus", hemozoin formation is complemented by other protective measures against heme, including a heme-binding antioxidant protein & unusually large amounts of a free-radical scavenger |
| UPDATE | 08.99 |
| AUTHOR | This data is not available for free |
| LITERATURE REF. | This data is not available for free |
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