Main > LIPID > Phosphocholines > Alkylphosphocholines

Product DE. A

PATENT ASSIGNEE'S COUNTRY Germany
UPDATE 02.00
PATENT ASSIGNEE ASTA Medica
PATENT CLAIMS 14-18C alkylphosphocholine prepn
- Reacting 14-18C n-alkanol with P oxychloride in presence
of halogenated hydrocarbon in single vessel
- Reacting prodt without isolation in halogenated hydrocar
bon with choline salt in presence of basic substance to
form phosphoric acid diester chloride
- Hydrolyzing phosphoric acid diester chloride to liberate
alkylphosphocholine crude prodt in organic phase
- Washing the organic phase at least one time with a solvent
comprising mixt selected from water & acid substance
- Separating the organic phase & evaporating the solvent
to obtain alkylphosphocholine crude prodt
- Suspending said crude prodt in saturated aliphatic ketone
woth > 3 C atoms
- Recovering the alkylphosphocholine
PATENT PHOTOCOPY Available on request

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