Main > DERMATOLOGY > Herpes Virus Infection > Treatment > Helicase. Primase. Inhibitor > BAY 57-1293

Product DE. Bp

STRUCTURE Thiazole-2-(SO2-NH2)-3-Me-5-[NMe-CO-CH2-C6H4-(2-
Pyridyl)]
FORMULATION Oral
MECHANISM OF ACTION Compd act on HSV's helicase/primase complex. HSV needs complex to untwist its double stranded DNA to form single strands & then prime the strands for replication into new viral DNA. Structure of complex is well characterized, making it a good target for designing inhibitors. The compd by binding to 2 targets simultaneously, mimic combination therapy with a single drug
OBSERVATION'S Hastens the healing of lesions in animal models
UPDATE 04.02
AUTHOR This data is not available for free
LITERATURE REF. This data is not available for free

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