STRUCTURE |
Thiazole-2-(SO2-NH2)-3-Me-5-[NMe-CO-CH2-C6H4-(2- Pyridyl)] |
FORMULATION | Oral |
MECHANISM OF ACTION | Compd act on HSV's helicase/primase complex. HSV needs complex to untwist its double stranded DNA to form single strands & then prime the strands for replication into new viral DNA. Structure of complex is well characterized, making it a good target for designing inhibitors. The compd by binding to 2 targets simultaneously, mimic combination therapy with a single drug |
OBSERVATION'S | Hastens the healing of lesions in animal models |
UPDATE | 04.02 |
AUTHOR | This data is not available for free |
LITERATURE REF. | This data is not available for free |
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