| SYNTHESIS |
work on screening a library of small-peptide catalysts to identify a pentapeptide that enantioselectively phosphorylates a derivative of myo-inositoThe catalyst leads to the preparation of D-myo-inositol-L-phosphate in a highly efficient manner without the aid of an enzymel, The new synthesis reduces the reliance on elaborate protecting-group strategies, chiral auxiliaries, and laborious purification steps, she adds, and should be useful as a model to develop additional selective, efficient phosphorylation methods that use enzyme mimics an important biologically active compound.
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