| METHOD |
The screening is a visual scan of the color of reflected light from 96-well titer plates in which various catalyst candidates have effected an enantioselective reaction. Author's method makes use of the fact that the degree of helical twist of molecular ordering in nematic liquid crystals is affected by chiral dopants. He uses a commercially available mixture, called E7, from EM Industries, Darmstadt, Germany. He makes derivatives of the chiral compounds with other liquid-crystal-forming molecules to use in doping E7.
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