Main > NUCLEIC ACID > Synthesis > Solid Phase Synthesis

Product DE. H.

PATENT ASSIGNEE'S COUNTRY Germany
UPDATE 08.99
PATENT ASSIGNEE Hoechst (Frankfurt/Main)
PATENT CLAIMS - Protecting exocyclic amino group of a nucleobase which
are present with a cyclic diacyl group
- Coupling the nucleobase to solid support
- Sequentially linking the nucleobase to other nucleobase,
in which exocyclic amino groups which are present on the
nucleobases being protected by a cyclic diacyl group to
form a protected oligonucleotide
- Deprotecting said protected oligonucleotide in the presen
ce of a strong nonnucleophilic base in organic solvent
PATENT PHOTOCOPY Available on request

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