| DESCRIPTION |
One way to carry out a combinatorial reaction with a ROMPgel is to synthesize a functionalized ROMP monomer, use it as a soluble reagent to carry out a transformation, and then polymerize it. Excess reagent, whether modified in the reaction or not, thus forms a polymer that falls out of solution, whereas the desired synthetic product stays in solution. This technique - which author calls "impurity annihilation"--permits solution-phase parallel synthesis to be carried out with minimal need for additional purification
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