Main > LIPID > Liposome > Dehydration. Storage. Rehydration

Product USA. L.

PATENT ASSIGNEE'S COUNTRY USA
UPDATE 07.99
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS Method for loading liposomes with charged material
- Prepn liposome prepn including liposomes having an ion
concn gradient capable of generating a transmembrane
potential having an orientation which will load the charged
material into the liposomes
- Dehydrating the liposome prepn
- Storing
- Rehydrating the dehydrated prepn
- Admixing charged material with the rehydrated prepn
Wherein the ion concn gradient is produced by encapsulating in the liposomes a first medium having a first concn of an ion, & then suspending the liposomes in second medium having second concn of the ion & the liposome prepn contains protective sugars at both inside & outside surfaces of the liposome membranes
PATENT PHOTOCOPY Available on request

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