Main > ORGANIC CHEMICALS > Chiral Organics > EnantioEnrichment. > Measurement. > Mass Spectrometric Method. > First Generation Method

Product DE. M

METHOD developed a mass spectrometric method based on isotopically labeled substrates. Reetz discovers and optimizes enantioselective catalysts through directed evolution. In his method, one enantiomer of a racemic substrate is labeled with deuterium. After the substrate reacts, the products of that enantiomer are differentiated from those of the other by their masses. The ee can be calculated from the parent peaks.

The system is completely automated.
UPDATE 06.02
AUTHOR Manfred T. Reetz, a chemistry professor at the Max Planck Institute for Coal Research
LITERATURE REF. This data is not available for free

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