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TECHNOLOGY is a high throughput chemical synthesis and screening methodology to generate peptides, peptidomimetics and small molecules on membranes. This proprietary technology is protected by global patents and enables synthesis of 2,000 to 20,000 molecules in parallel in a fully automated process developed at Jerini. The molecules are then screened for binding to the target protein either directly on membranes or are released from the membrane for HTS screening. SPOT™ strongly supports extensive pharmacophore mapping ­ thousands of derivatives of a peptide lead molecule are readily synthesized and screened - as a prerequisite for its transformation into a peptidomimetic or small molecule
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