| MECHANISM OF ACTION |
In response to stressful life events, individuals carrying the short version of an allele in the promoter region of the gene for the serotonin transporter, 5-HTT, are more likely to develop depression and to consider or attempt suicide than those who have the long version. The serotonin transporter retrieves serotonin after it's been released into the synapse. SSRI antidepressants block this transporter |
| UPDATE | 02.04 |
| AUTHOR | Terrie E. Moffitt, a professor of social behavior and development at King's College London, and colleagues |
| LITERATURE REF. | Science, 301, 386 (2003) |
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