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Product Denmark. S

PATENT ASSIGNEE'S COUNTRY Denmark
UPDATE 09.99
PATENT ASSIGNEE This data is not available for free
PATENT CLAIMS Protein which is
- Protein which is purified, & which is released from metaboli
zing mycobacteria belonging to the tuberculosis complex &
can be isolated from filtrates from such mycobacteria grown
as shaken cultures for 7 days, & has MW 3-16 kDa as de
termined by SDS-PAGE & Ag staining
Which protein induces a release of IFN-gamma of > 1500 pg/ml from reactivated memory T-lymphocytes withdrawn from a C57B1/6j mouse within 4 days after the mouse has been rechallenge infected with said mycobacteria, the induction performed by the addition of said protein to a suspension comprising 200,000 reactivated memory T-cells per ml, the addition of protein resulting in a concn of 1 micro.g per ml of suspension, the release of IFN-gamma being assessable by determn of IFN-gamma in supernatant harvested 2 days after the addition of the protein to suspension
Said protein having the ability of eliciting a delayed type hypersensitivity reaction
PATENT PHOTOCOPY Available on request

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