Main > ORGAN. TISSUE. ENGINEERING > Scaffold > Polymer. > Calcium Alginate HydroGel > Org.: USA. C. (Research) > Work Description

---

Microfluidic biomaterial
Most materials used for bio-medical applications lack a way to modulate the concentration of soluble species within their bulk, a function served in living tissue by the vascular system. Author and coworkers have constructed a “microfluidic biomaterial” that consists of a network of channels in a calcium alginate hydrogel. The device is sturdy and impermeable enough to contain distinct flow paths, yet permeable enough for materials to diffuse through it. Using solutions of fluorescein or fluorescently labeled dextran, Author and coworkers show that soluble species can diffuse between the channels and the bulk, providing a way to deliver or extract them. A pressure-driven flow through the channels speeds up mass transfer through the device. Author hopes to use such a device as a physiologically accurate scaffold for tissue engineering by seeding cells into the bulk material.




Work Description's products
This section has no products